The National Health Service (NHS) has alerted the public that a sudden “pale” appearance could signal a need to consult a doctor, especially if this is unusual for an individual or if it accompanies other worrying symptoms. Acute myeloid leukaemia (AML) is a fast-progressing and aggressive condition that typically necessitates immediate treatment, as stated on the NHS information page.
Health experts explain that AML is classified based on the affected white blood cells, which include monocytes and granulocytes from myeloid stem cells, and lymphocytes from lymphoid stem cells.
While AML mainly impacts individuals over 75 years old, it is a relatively uncommon cancer type, with about 3,100 new cases diagnosed annually in the UK. Knowing when to see a General Practitioner (GP) is crucial.
Symptoms of AML tend to emerge gradually over a few weeks and worsen over time. Individuals are advised to schedule an appointment with their GP if they or their child exhibit potential AML symptoms, emphasizing the importance of investigating these symptoms even though leukaemia is unlikely.
If leukaemia is suspected, the GP may conduct blood tests to assess blood cells. If abnormalities are detected, a referral to a haematologist for further urgent tests and treatment may be arranged.
The cause of AML is often unknown, with many cases having no identifiable trigger. However, certain factors can heighten the risk of developing AML, including lifestyle choices and genetic predispositions.